Definition

Bioavailability refers to the proportion of a nutrient or compound that is absorbed and utilized by the body after administration. It depends on factors including molecular form, delivery method, digestive function, nutrient cofactors, and individual physiology. High bioavailability means more of the substance reaches systemic circulation to exert its effects.

Why It Matters

Taking a supplement doesn't guarantee your body absorbs and uses it. Bioavailability determines whether a nutraceutical is effective. Factors like chelation (minerals), liposomal delivery, absorption enhancers, and taking with or without food significantly impact how much benefit you receive from supplements.

Related Conditions

Fatigue Anemia Vitamin D Deficiency Malabsorption Ibs

Related Modalities

Nutraceuticals Clinical Nutrition Functional Lab Testing

Frequently Asked Questions

Strategies include choosing highly bioavailable forms (methylated B vitamins, chelated minerals), taking fat-soluble vitamins with meals containing fat, using liposomal or sublingual delivery, pairing with absorption enhancers (black pepper with turmeric), and optimizing digestive function.

Manufacturers highlight bioavailability when their product uses superior forms that are better absorbed than standard versions—like magnesium glycinate vs. magnesium oxide, or curcumin with piperine. This indicates quality and justifies higher cost compared to poorly absorbed alternatives.