Gut-Brain Axis
Definition
The gut-brain axis is the bidirectional communication network between the gastrointestinal tract and the central nervous system, mediated by neural, hormonal, and immunological pathways. The gut microbiome produces neurotransmitters (serotonin, GABA, dopamine), influences inflammation, and communicates with the brain via the vagus nerve, affecting mood, cognition, and behavior.
Why It Matters
Over 90% of serotonin is produced in the gut. Gut dysbiosis, inflammation, and leaky gut directly impact mental health, contributing to anxiety, depression, brain fog, and neurodegenerative disease. Healing the gut through diet, probiotics, and lifestyle changes can dramatically improve mental and cognitive health.
Related Conditions
Related Modalities
Frequently Asked Questions
The gut produces neurotransmitters, regulates inflammation, influences stress hormones, and communicates with the brain via the vagus nerve. Dysbiosis and gut inflammation trigger systemic inflammation that affects brain function, neurotransmitter production, and mood regulation.
Many people experience significant improvements in mood, anxiety, and cognition by addressing gut dysfunction. Probiotics, anti-inflammatory nutrition, gut healing protocols, and stress management support the gut-brain axis. For complex mental health conditions, gut support complements rather than replaces conventional treatment.
Dr. Sanika Kshirsagar, ND
Doctorate of Naturopathic Medicine (ND)
Bastyr University, Kenmore, WA
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