Insulin Resistance
Definition
Insulin resistance is a condition in which cells in the body become less responsive to insulin, requiring the pancreas to produce more insulin to maintain normal blood sugar levels. Over time, this can lead to elevated blood sugar, weight gain, hormonal imbalances, and increased risk of type 2 diabetes and cardiovascular disease.
Why It Matters
Insulin resistance is a root cause of many chronic conditions including PCOS, metabolic syndrome, type 2 diabetes, and cardiovascular disease. It also disrupts reproductive hormones, contributing to irregular cycles, infertility, and difficulty losing weight. Early identification and intervention can reverse insulin resistance and prevent progression.
Related Conditions
Related Modalities
Frequently Asked Questions
Common signs include difficulty losing weight, cravings for sugar and carbs, fatigue after meals, darkened skin patches (acanthosis nigricans), abdominal weight gain, irregular periods, and elevated fasting blood sugar or insulin levels on lab testing.
Treatment includes a blood sugar-balancing diet low in refined carbs, regular movement and strength training, stress management, sleep optimization, supplements like inositol, berberine, chromium, and alpha-lipoic acid, and addressing underlying factors like inflammation and gut health.

Dr. Sanika Kshirsagar, ND
Doctorate of Naturopathic Medicine (ND)
Bastyr University, Kenmore, WA
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