Microbiome
Definition
The microbiome refers to the trillions of microorganisms—bacteria, fungi, viruses, and other microbes—that live in and on the human body, particularly in the gut. The gut microbiome plays essential roles in digestion, immune function, hormone metabolism, neurotransmitter production, and overall health.
Why It Matters
A healthy, diverse microbiome is foundational to wellness. Dysbiosis—an imbalance in the microbiome—contributes to digestive issues, autoimmune conditions, hormonal imbalances, mental health disorders, and chronic inflammation. Supporting microbiome health through diet, probiotics, and lifestyle is a cornerstone of naturopathic medicine.
Related Conditions
Related Modalities
Frequently Asked Questions
Improve microbiome health with a diverse, fiber-rich diet including fermented foods (sauerkraut, kimchi, yogurt), prebiotics (onions, garlic, asparagus), probiotics, avoiding unnecessary antibiotics, managing stress, sleeping well, and reducing processed foods and sugar.
The microbiome influences hormone metabolism through the estrobolome (bacteria that regulate estrogen), production of short-chain fatty acids that reduce inflammation, and modulation of cortisol and insulin. An imbalanced microbiome can contribute to estrogen dominance, PCOS, and thyroid dysfunction.

Dr. Sanika Kshirsagar, ND
Doctorate of Naturopathic Medicine (ND)
Bastyr University, Kenmore, WA
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